Crosstalk between proximal tubular epithelial cells and other interstitial cells in tubulointerstitial fibrosis after renal injury

The energy needs of tubular epithelial components, especially proximal tubular epithelial cells (PTECs), are high and they heavily depend on aerobic metabolism. As a result, they are particularly vulnerable to various injuries caused by factors such as ischemia, proteinuria, toxins, and elevated glu...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Congcong Guo, Yuying Cui, Mingwen Jiao, Jinming Yao, Junyu Zhao, Yutian Tian, Jianjun Dong, Lin Liao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	tubulointerstitial fibrosis crosstalk chronic kidney disease proximal tubular epithelial cells molecular mechanism
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1256375/full