Antinociceptive effects of Cremophor EL orally administered to mice

Surfactants are frequently used to improve solubilization of lipophilic drugs. Cremophor EL (CrEL) is a polyoxyethylated castor oil surfactant used to solubilize water-insoluble drugs such as anesthetic, antineoplastic, immunosuppressive and analgesic drugs, vitamins and new synthetic compounds, inc...

Full description

Bibliographic Details
Published in:Brazilian Journal of Medical and Biological Research
Main Authors: Z. Tabarelli, D.B. Berlese, P.D. Sauzem, C.F. Mello, M.A. Rubin
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2003-01-01
Subjects:
Antinociception
Cremophor EL
Tail immersion test
Writhing test
Dipyrone
Morphine
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000100016

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000100016

Similar Items