FLT3/ITD associated with an immature immunophenotype in PML-RARα leukemia

Acute promyelocytic leukemia (APL) is characterized by the specific PML-RARa fusion gene resulting from translocation t(15;17) (q22;q12). Internal tandem duplication (ITD) of the <em>FLT3</em> gene has been observed in approximately 35% of APLs, and large-scale studies have identified th...

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Bibliographic Details

Published in:	Hematology Reports
Main Authors:	Mariko Takenokuchi, Seiji Kawano, Yuji Nakamachi, Yasuyuki Sakota, Meilani Syampurnawati, Katsuyasu Saigo, Eiji Tatsumi, Shunichi Kumagai
Format:	Article
Language:	English
Published:	MDPI AG 2012-10-01
Subjects:	FLT3/ITD, FLT3/ D835, CD2, immature phenotype
Online Access:	http://www.pagepress.org/journals/index.php/hr/article/view/4380