Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine

Introduction Characterised by chronic inflammation of the gastrointestinal tract, inflammatory bowel disease (IBD) symptoms including diarrhoea, abdominal pain and fatigue can significantly impact patient’s quality of life. Therapeutic developments in the last 20 years have revolutionised treatment....

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Bibliographic Details

Published in:	BMJ Open
Main Authors:	Peter M Irving, Miles Parkes, Ruth Wood, Ailsa L Hart, Nicholas A Kennedy, Nick Powell, Julian R Marchesi, Tariq Ahmad, Tim Raine, Andrew King, James O Lindsay, Kevin Whelan, Charlie W Lees, Christopher A Lamb, Jack Satsangi, Emma Clark, Shriya Sharma, Xinyue Zhang, Christopher J Stewart, Naomi McGregor, Helen C Hancock, Rebecca H Maier, John C Mansfield, Mary Doona, Michelle Bardgett, Natalie J Prescott, Trevor Liddle, Robert Lees, Hannah Watson, Carl A Anderson, Ally Speight, Ciara Kennedy, Sarah Lawrence, Nicola J Wyatt, Jennifer A Doyle, Rebecca E McIntyre, Luke Jostins-Dean, Victoria Hildreth, James MS Wason, Dean Allerton, Dawn Clewes, Cristina Cotobal Martin, Katherine Frith, Sameena Iqbal, Laura Letchford, Jasmin Ostermayer, Tolulope Osunnuyi, Tara Shrestha, Michelle Strickland, Gregory R Young
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2024-04-01
Online Access:	https://bmjopen.bmj.com/content/14/4/e073639.full