Structural and Functional Integration of Tissue-Nonspecific Alkaline Phosphatase Within the Alkaline Phosphatase Superfamily: Evolutionary Insights and Functional Implications

Phosphatases are enzymes that catalyze the hydrolysis of phosphate esters. They play critical roles in diverse biological processes such as extracellular nucleotide homeostasis, transport of molecules across membranes, intracellular signaling pathways, or vertebrate mineralization. Among them, tissu...

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Bibliographic Details

Published in:	Metabolites
Main Authors:	Iliass Imam, Gilles Jean Philippe Rautureau, Sébastien Violot, Eva Drevet Mulard, David Magne, Lionel Ballut
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Subjects:	tissue-nonspecific alkaline phosphatase (TNAP) alkaline phosphatase (AP) superfamily ectonucleotide pyrophosphatases/phosphodiesterases (ENPP) arylsulfatases (ARS)
Online Access:	https://www.mdpi.com/2218-1989/14/12/659