Recognition of Dimeric Lewis X by Anti-Dimeric Le<sup>x</sup> Antibody SH2

The carbohydrate antigen dimeric Lewis X (DimLe<sup>x</sup>), which accumulates in colonic and liver adenocarcinomas, is a valuable target to develop anti-cancer therapeutics. Using the native DimLe<sup>x</sup> antigen as a vaccine would elicit an autoimmune response against...

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Bibliographic Details
Published in:Vaccines
Main Authors: Sinthuja Jegatheeswaran, Ari Asnani, Adam Forman, Jenifer L. Hendel, Christopher J. Moore, Ali Nejatie, An Wang, Jo-Wen Wang, France-Isabelle Auzanneau
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Subjects:
tumor-associated carbohydrate antigens
ELISA
dimeric Lewis X
SH2
conformational epitope
Online Access:https://www.mdpi.com/2076-393X/8/3/538

Internet

https://www.mdpi.com/2076-393X/8/3/538

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