B cell subsets reconstitution and immunoglobulin levels in children and adolescents with B non-Hodgkin lymphoma after treatment with single anti CD20 agent dose included in chemotherapeutic protocols: single center experience and review of the literature

Background. RTX, an anti-CD20 monoclonal antibody, added to chemotherapy has proven to be effective in children and adolescents with high-grade, high-risk and matured non-Hodgkin lymphoma. RTX leads to prompt CD19+ B lymphocyte depletion. However, despite preserved immunoglobulin production by long-...

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Bibliographic Details

Published in:	Biomedical Papers
Main Authors:	Eva Hlavackova, Zdenka Krenova, Arpad Kerekes, Peter Slanina, Marcela Vlkova
Format:	Article
Language:	English
Published:	Palacký University Olomouc, Faculty of Medicine and Dentistry 2024-06-01
Subjects:	rituximab b non-hodgkin lymphoma chemotherapy late complications of chemotherapy hypogammaglobulinemia children and adolescents
Online Access:	https://biomed.papers.upol.cz/artkey/bio-202402-0010_b-cell-subsets-reconstitution-and-immunoglobulin-levels-in-children-and-adolescents-with-b-non-hodgkin-lymphoma.php