Hydrophilic Tetraphenylethene-Based Tetracationic Cyclophanes: NADPH Recognition and Cell Imaging With Fluorescent Switch

A hydrophilic TPE-based tetracationic cyclophane TPE-cyc was synthesized, which could capture intracellular Nicotinamide adenine dinucleotide phosphate and fuel the antioxidative ability of tumor cells to detoxify reactive oxygen species (ROS). Meanwhile, upon the reduction by cellular GSH, TPE-cyc...

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Bibliographic Details

Published in:	Frontiers in Chemistry
Main Authors:	Dan Wu, Zhankui Zhang, Xinyang Yu, Bing Bai, Shaolong Qi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-12-01
Subjects:	tetracationic cyclophanes tetraphenylethene NADPH recognition host-guest complexation fluorescent switch
Online Access:	https://www.frontiersin.org/articles/10.3389/fchem.2021.817720/full