ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7

Abstract The contributions of aberrantly expressed metabolic enzymes to gastric cancer (GC) initiation and progression have been widely appreciated in recent years. Acetyl-CoA acetyltransferase 2 (ACAT2) is one member of the acetyl- CoA thiolase family. Previous studies demonstrated that ACAT2 eithe...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cell Death and Disease
المؤلفون الرئيسيون: Mengmeng Zhang, Fenglin Cai, Jiamei Guo, Siya Liu, Gang Ma, Mingzhi Cai, Rupeng Zhang, Jingyu Deng
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Publishing Group 2024-04-01
الوصول للمادة أونلاين:https://doi.org/10.1038/s41419-024-06666-x