RNA-seq and Tn-seq reveal fitness determinants of vancomycin-resistant Enterococcus faecium during growth in human serum

Abstract Background The Gram-positive bacterium Enterococcus faecium is a commensal of the human gastrointestinal tract and a frequent cause of bloodstream infections in hospitalized patients. The mechanisms by which E. faecium can survive and grow in blood during an infection have not yet been char...

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Bibliographic Details

Published in:	BMC Genomics
Main Authors:	Xinglin Zhang, Vincent de Maat, Ana M. Guzmán Prieto, Tomasz K. Prajsnar, Jumamurat R. Bayjanov, Mark de Been, Malbert R. C. Rogers, Marc J. M. Bonten, Stéphane Mesnage, Rob J. L. Willems, Willem van Schaik
Format:	Article
Language:	English
Published:	BMC 2017-11-01
Subjects:	Enterococcus faecium Transcriptome Transposon mutant library screening Nucleotide biosynthesis Carbohydrate metabolism Virulence
Online Access:	http://link.springer.com/article/10.1186/s12864-017-4299-9