Induction of Temporal Lobe Epilepsy in Mice with Pilocarpine

In the pilocarpine model of temporal lobe epilepsy (TLE) in rodents, systemic injections of pilocarpine induce continuous, prolonged limbic seizures, a condition termed “Status Epilepticus” (SE). With appropriate doses, many inbred strains of mice show behavioral seizures within an hour after piloc...

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Bibliographic Details
Published in:Bio-Protocol
Main Authors: Muhammad Arshad, Janice Naegele
Format: Article
Language:English
Published: Bio-protocol LLC 2020-02-01
Online Access:https://bio-protocol.org/en/bpdetail?id=3533&type=0