STING modulates HBV-related acute-on-chronic liver failure by mediating autophagy and macrophage polarization

Background & Aims: HBV-related acute-on-chronic liver failure (HBV-ACLF) is a severe acute liver injury secondary to HBV-related chronic liver disease (with or without cirrhosis) and is characterized by a high short-term mortality rate. Presently, there is a paucity of experimental models th...

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Bibliographic Details

Published in:	Immunobiology
Main Authors:	Hao Zhang, Teng Liang, Wanlu Duan, Futing Liu, LiPing Li, Qian Liu, Jianfei Li, Qiyin Zong, Lei Jin, Qin Wang, Qiang Zhou
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Subjects:	HBV-related acute-on-chronic liver failure Interferon gene stimulator protein Autophagy
Online Access:	http://www.sciencedirect.com/science/article/pii/S0171298524000780