Low‐fat hypocaloric diet reduces neprilysin in overweight and obese human subjects

Abstract Aims Neprilysin (NEP), a zinc metallopeptidase, degrades a variety of bioactive peptides including natriuretic peptides terminating their biological action on arterial blood pressure and natriuresis. Pharmacological inhibition of NEP reduces mortality in patients with heart failure with red...

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Bibliographic Details

Published in:	ESC Heart Failure
Main Authors:	Christine Henke, Sven Haufe, Doreen Ziehl, Stefan R. Bornstein, Jeanette Schulz‐Menger, Martin Heni, Stefan Engeli, Jens Jordan, Andreas L. Birkenfeld
Format:	Article
Language:	English
Published:	Wiley 2021-04-01
Subjects:	Neprilysin Hypocaloric low‐fat diet Natriuretic peptides Heart failure
Online Access:	https://doi.org/10.1002/ehf2.13220