Prolonged intermittent theta burst stimulation restores the balance between A2AR- and A1R-mediated adenosine signaling in the 6-hydroxidopamine model of Parkinson’s disease

An imbalance in adenosine-mediated signaling, particularly the increased A2AR-mediated signaling, plays a role in the pathogenesis of Parkinson’s disease. Existing therapeutic approaches fail to alter disease progression, demonstrating the need for novel approaches in PD. Repetitive transcranial mag...

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Bibliographic Details

Published in:	Neural Regeneration Research
Main Authors:	Milica Zeljkovic Jovanovic, Jelena Stanojevic, Ivana Stevanovic, Milica Ninkovic, Tihomir V. Ilic, Nadezda Nedeljkovic, Milorad Dragic
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2025-07-01
Subjects:	a1r a2ar adenosine receptors adenosine ecto-5′-nucleotidase intermittent theta burst stimulation non-invasive brain stimulation parkinson’s disease purinergic signalling
Online Access:	https://journals.lww.com/10.4103/NRR.NRR-D-23-01542