Computer aided design of novel antibiotic drug candidate against multidrug resistant strains of Salmonella typhi from pyridine-substituted coumarins

Abstract Background The rising cases of resistance to existing antibiotics by Salmonella typhi, has made the development of novel drug candidates a necessity. In this study, a data set of antibacterial pyridine substituted coumarins were subjected to Virtual Screening against SipA effector protein o...

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Bibliographic Details
Published in:Beni-Suef University Journal of Basic and Applied Sciences
Main Authors: Philip John Ameji, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba
Format: Article
Language:English
Published: SpringerOpen 2024-02-01
Subjects:
Typhoid fever
SipA
DFT
In-silico
Salmonella typhi
Online Access:https://doi.org/10.1186/s43088-024-00473-1

Internet

https://doi.org/10.1186/s43088-024-00473-1

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