A systematic review of the protective effects of silymarin/silibinin against doxorubicin-induced cardiotoxicity

Abstract Purpose Although doxorubicin chemotherapy is commonly applied for treating different malignant tumors, cardiotoxicity induced by this chemotherapeutic agent restricts its clinical use. The use of silymarin/silibinin may mitigate the doxorubicin-induced cardiac adverse effects. For this aim,...

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Bibliographic Details
Published in:Cancer Cell International
Main Authors: Mandeep Singh, Mustafa M. Kadhim, Abduladheem Turki Jalil, Shamam Kareem Oudah, Zafar Aminov, Fahad Alsaikhan, Zanko Hassan Jawhar, Andrés Alexis Ramírez-Coronel, Bagher Farhood
Format: Article
Language:English
Published: BMC 2023-05-01
Subjects:
Online Access:https://doi.org/10.1186/s12935-023-02936-4