Testosterone Deficiency Promotes Hypercholesteremia and Attenuates Cholesterol Liver Uptake via AR/PCSK9/LDLR Pathways

Background. Testosterone deficiency is reportedly correlated with an elevation of cholesterol in plasma, but the mechanism remains unclear. Our objective was to investigate the effects of testosterone deficiency on cholesterol metabolism and the corresponding molecular changes in vivo and in vitro....

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Bibliographic Details

Published in:	International Journal of Endocrinology
Main Authors:	Yu Yuefeng, Lin Zhiqi, Chen Yi, Zhu Keyu, Wan Heng, Wang Yuying, Wang Ningjian, Yu Yuetian, Gu Xinjie, Zhang Yihao, Lu Yingli, Xia Fangzhen
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Online Access:	http://dx.doi.org/10.1155/2022/7989751