The COMPASS complex maintains the metastatic capacity imparted by a subpopulation of cells in UPS

Summary: Intratumoral heterogeneity is common in cancer, particularly in sarcomas like undifferentiated pleomorphic sarcoma (UPS), where individual cells demonstrate a high degree of cytogenic diversity. Previous studies showed that a small subset of cells within UPS, known as the metastatic clone (...

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Bibliographic Details

Published in:	iScience
Main Authors:	Ga I. Ban, Vijitha Puviindran, Yu Xiang, Puvi Nadesan, Jackie Tang, Jianhong Ou, Nicholas Guardino, Makoto Nakagawa, MaKenna Browne, Asjah Wallace, Koji Ishikawa, Eijiro Shimada, John T. Martin, Yarui Diao, David G. Kirsch, Benjamin A. Alman
Format:	Article
Language:	English
Published:	Elsevier 2024-07-01
Subjects:	Epigenetics Cancer Genomics Transcriptomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224014123