Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

Abstract Insulin deficiency in type 1 diabetes (T1D) is generally considered a consequence of immune‐mediated specific beta‐cell loss. Since healthy pancreatic islets consist of ~65% beta cells, this would lead to reduced islet size, while the number of islets per pancreas volume (islet density) wou...

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Bibliographic Details

Published in:	The Journal of Pathology: Clinical Research
Main Authors:	Peter Seiron, Anna Wiberg, Enida Kuric, Lars Krogvold, Frode L Jahnsen, Knut Dahl‐Jørgensen, Oskar Skog, Olle Korsgren
Format:	Article
Language:	English
Published:	Wiley 2019-10-01
Subjects:	type 1 diabetes human pancreas
Online Access:	https://doi.org/10.1002/cjp2.140