Targeted Genome Mining—From Compound Discovery to Biosynthetic Pathway Elucidation

Natural products are an important source of novel investigational compounds in drug discovery. Especially in the field of antibiotics, Actinobacteria have been proven to be a reliable source for lead structures. The discovery of these natural products with activity- and structure-guided screenings h...

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Bibliographic Details

Published in:	Microorganisms
Main Authors:	Nils Gummerlich, Yuriy Rebets, Constanze Paulus, Josef Zapp, Andriy Luzhetskyy
Format:	Article
Language:	English
Published:	MDPI AG 2020-12-01
Subjects:	angucyclinone heterologous expression natural products Actinobacteria biosynthesis
Online Access:	https://www.mdpi.com/2076-2607/8/12/2034