The Effect of Gastric Bypass and Sleeve Gastrectomy Surgery on the Level of Vitamin A, Iron, Copper, Ferritin, Hemoglobin, Vitamin D, Vitamin B12, Zinc and Cardiometabolic Factors in Patients with Morbid Obesity

Background: Obesity is a significant global health issue and bariatric surgery has emerged as a critical intervention for sustainable weight loss and metabolic improvement in individuals with severe obesity. Sleeve Gastrectomy (SG) and Roux-en-Y Gastric Bypass (RYGB) are the most commonly performed...

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Bibliographic Details
Published in:International Journal of Nutrition Sciences
Main Authors: Gholamreza Moradpour, Mohammadreza Minaei, Neda Haghighat, Seyedeh Mahboobeh Hashemi, Nader Moeinvaziri, Babak Hosseini, Bisma Zulfaqar, Fatemeh Saeedi, Reza Gholami, Faraneh Arabi, Maryam Asakereh, Masood Amini
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2025-09-01
Subjects:
obesity
weight
bariatric surgery
sleeve gastrectomy
roux-en-y gastric bypass
Online Access:https://ijns.sums.ac.ir/article_51092_cf3bb6471492527b5329ac13e823cb3e.pdf
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Summary:Background: Obesity is a significant global health issue and bariatric surgery has emerged as a critical intervention for sustainable weight loss and metabolic improvement in individuals with severe obesity. Sleeve Gastrectomy (SG) and Roux-en-Y Gastric Bypass (RYGB) are the most commonly performed procedures, each with distinct mechanisms and outcomes. Comparative studies have highlighted varying outcomes between SG and RYGB, particularly in terms of weight loss, metabolic improvement, and postoperative complications. This study aimed to compare the baseline characteristics and subsequent outcomes of patientsundergoing SG and RYGB.Methods: Weight loss, metabolic parameters, and several micronutrient levels including biochemical factors, lipid profile, vitamin A, Iron, copper, ferritin, hemoglobin, vitamin D, vitamin B12 and zinc over a 12-month follow-up period were compared in both groups.Results: Both SG as well as RYGB led to substantial weight loss and improvement in lipid profile and glycemic control over 12 months. RYGB showed superior reductions in LDL cholesterol and total cholesterol compared to SG, indicating potential additional benefits of RYGB.Conclusion: Both SG and RYGB were effective for weight loss and metabolic improvement, with RYGB showing superior long-term benefits in lipid profile management.
ISSN:2538-1873
2538-2829

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