Mitophagy and cGAS–STING crosstalk in neuroinflammation

Mitophagy, essential for mitochondrial health, selectively degrades damaged mitochondria. It is intricately linked to the cGAS–STING pathway, which is crucial for innate immunity. This pathway responds to mitochondrial DNA and is associated with cellular stress response. Our review explores the mole...

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Bibliographic Details

Published in:	Acta Pharmaceutica Sinica B
Main Authors:	Xiaogang Zhou, Jing Wang, Lu Yu, Gan Qiao, Dalian Qin, Betty Yuen-Kwan Law, Fang Ren, Jianming Wu, Anguo Wu
Format:	Article
Language:	English
Published:	Elsevier 2024-08-01
Subjects:	Neuroinflammation Mitophagy cGAS–STING Innate immunity Mitochondrial DNA Crosstalk
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211383524001904