Veillonella and Streptococcus are associated with aging of the gut microbiota and affect the efficacy of immune checkpoint inhibitors

IntroductionThe rapid increase in the number of elderly patients with cancer necessitates treatment strategies based on the effects of aging because of drastic side effects of cytotoxic anticancer agents. Immune checkpoint inhibitors (ICIs) are relatively less toxic and can be easily administered to...

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出版年:	Frontiers in Immunology
主要な著者:	Yuya Hirasawa, Junya Isobe, Masahiro Hosonuma, Toshiaki Tsurui, Yuta Baba, Eiji Funayama, Kohei Tajima, Masakazu Murayama, Yoichiro Narikawa, Hitoshi Toyoda, Midori Shida, Aya Sasaki, Yuuki Maruyama, Yasunobu Amari, Emiko Mura, Risako Suzuki, Nana Iriguchi, Tomoyuki Ishiguro, Ryotaro Ohkuma, Masahiro Shimokawa, Hirotsugu Ariizumi, Yutaro Kubota, Atsushi Horiike, Takehiko Sambe, Naoki Uchida, Satoshi Wada, Shinichi Kobayashi, Yuji Kiuchi, Atsuo Kuramasu, Kiyoshi Yoshimura, Takuya Tsunoda
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2025-05-01
主題:	gut microbiota immune checkpoint inhibitor aging Veillonella Streptococcus
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1528521/full