Characterisation of naturally occurring isothiocyanates as glutathione reductase inhibitors

Glutathione reductase (GR), an essential antioxidant enzyme against oxidative stress, has become an attractive drug target for the development of anticancer and antimalarial drugs. In this regard, we evaluated the naturally occurring isothiocyanates as promising GR inhibitors and elucidated the mech...

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Bibliographic Details

Published in:	Journal of Enzyme Inhibition and Medicinal Chemistry
Main Authors:	Xia Li, Maowei Ni, Xiaoling Xu, Wei Chen
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-01-01
Subjects:	glutathione reductase isothiocyanate inhibitor thiocarbamoylation
Online Access:	http://dx.doi.org/10.1080/14756366.2020.1822828