Effects of cannabidiol, with and without ∆9-tetrahydrocannabinol, on anxiety-like behavior following alcohol withdrawal in mice

IntroductionAlcohol use disorder (AUD) is commonly associated with anxiety disorders and enhanced stress-sensitivity; symptoms that can worsen during withdrawal to perpetuate continued alcohol use. Alcohol increases neuroimmune activity in the brain. Our recent evidence indicates that alcohol direct...

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Bibliographic Details

Published in:	Frontiers in Neuroscience
Main Authors:	Mariam Melkumyan, Vibha M. Annaswamy, Alexandra M. Evans, Opeyemi F. Showemimo, Zari E. McCullers, Dongxiao Sun, Terrence E. Murphy, Kent E. Vrana, Amy C. Arnold, Wesley M. Raup-Konsavage, Yuval Silberman
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-06-01
Subjects:	alcohol withdrawal anxiety Cannabidiol (CBD) ∆9-tetrahydrocannabinol (THC) open field test microglia
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2024.1375440/full