HIV-1 latency reversal agent boosting is not limited by opioid use

Opioid use may affect the HIV-1 reservoir and its reversal from latency. We studied 47 virally suppressed people with HIV (PWH) and observed that lower concentration of HIV-1 latency reversal agents (LRAs), used with small molecules that did not reverse latency, synergistically increased the magnitu...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Tyler Lilie, Jennifer Bouzy, Archana Asundi, Jessica Taylor, Samantha Roche, Alex Olson, Kendyll Coxen, Heather Corry, Hannah Jordan, Kiera Clayton, Nina Lin, Athe Tsibris
Format: Article
Language:English
Published: American Society for Clinical investigation 2024-11-01
Subjects:
AIDS/HIV
Immunology
Online Access:https://doi.org/10.1172/jci.insight.185480

Internet

https://doi.org/10.1172/jci.insight.185480

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