Engineering Yarrowia lipolytica for high-level β-elemene production via combinatorial metabolic strategies

β-Elemene, a pharmacologically active sesquiterpene derived from the traditional Chinese medicinal herb Curcuma wenyujin, exhibits broad-spectrum anti-tumor and anti-inflammatory activities. Currently, its commercial production relies heavily on plant extraction, a process associated with high costs...

Full description

Bibliographic Details

Published in:	Synthetic and Systems Biotechnology
Main Authors:	Mingyu Dai, Qingyi Cao, Shuanglong Jia, Jiang Chen, Hui-Ying Xu, Bang-Ce Ye, Wei-Bing Liu, Ying Zhou
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2025-12-01
Subjects:	β-elemene Germacrene A Sesquiterpene Metabolic engineering Yarrowia lipolytica
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405805X25000924