TFE3-mediated lysosomal biogenesis and homeostasis alleviates arsenic-induced lysosomal and immune dysfunction in macrophages
Arsenic is a prevalent environmental toxin associated with cancer that disrupts the immune surveillance and defense functions of macrophages. The MiT/TFE family plays a crucial role in maintaining lysosomal biogenesis and homeostasis, with TFE3 being ubiquitously expressed across most immune cell ty...
| 发表在: | Ecotoxicology and Environmental Safety |
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| Main Authors: | , , , , , , , , , |
| 格式: | 文件 |
| 语言: | 英语 |
| 出版: |
Elsevier
2025-07-01
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| 主题: | |
| 在线阅读: | http://www.sciencedirect.com/science/article/pii/S0147651325007109 |