IBD-associated TL1A gene (TNFSF15) haplotypes determine increased expression of TL1A protein.

<h4>Background</h4>The recently identified member of the TNF superfamily TL1A (TNFSF15) increases IFN-gamma production by T cells in peripheral and mucosal CCR9+ T cells. TL1A and its receptor DR3 are up-regulated during chronic intestinal inflammation in ulcerative colitis and Crohn...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Kathrin S Michelsen, Lisa S Thomas, Kent D Taylor, Qi T Yu, Ling Mei, Carol J Landers, Carrie Derkowski, Dermot P B McGovern, Jerome I Rotter, Stephan R Targan
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2009-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0004719&type=printable