Mechanism of modified mRNA structure in COVID-19 vaccines for inducing neutralizing antibodies

The development of SARS-CoV-2 mRNA vaccines is closely linked to advancements in mRNA manufacturing technology. Structural modifications, such as replacing uridine with 1-methylpseudouridine (1mψ), enhance translation efficiency and help the mRNA evade immune detection. Lipid nanoparticles (LNPs) s...

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Bibliographic Details

Published in:	Acta Biochimica Indonesiana
Main Authors:	Sabighoh Zanjabila, Beti Ernawati Dewi
Format:	Article
Language:	English
Published:	Indonesian Society for Biochemistry and Molecular Biology 2024-10-01
Subjects:	mRNA vaccine neutralizing antibody SARS-CoV-2
Online Access:	https://pbbmi.org/newjurnal/index.php/actabioina/article/view/121