Synthesis and Investigation of Flavanone Derivatives as Potential New Anti-Inflammatory Agents

Flavonoids are polyphenols with broad known pharmacological properties. A series of 2,3-dihydroflavanone derivatives were thus synthesized and investigated for their anti-inflammatory activities. The target flavanones were prepared through cyclization of 2′-hydroxychalcone derivatives, the later obt...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Cynthia Sinyeue, Mariko Matsui, Michael Oelgemöller, Frédérique Bregier, Vincent Chaleix, Vincent Sol, Nicolas Lebouvier
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Subjects:	flavanone anti-inflammatory activity structure–activity relationship (SAR) RAW264.7 pinocembrin
Online Access:	https://www.mdpi.com/1420-3049/27/6/1781