PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: a potential treatment for age related macular degeneration

Age-related macular degeneration (AMD) is a chronic, progressive retinal disease characterized by an inflammatory response mediated by activated macrophages and microglia infiltrating the inner layer of the retina. In this study, we demonstrate that inhibition of macrophages through Siglec binding i...

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發表在:	Frontiers in Immunology
Main Authors:	Anitha Krishnan, Victor G. Sendra, Diyan Patel, Amit Lad, Michelle K. Greene, Peter Smyth, Samantha A. Gallaher, Úna M. Herron, Christopher J. Scott, Mohamed Genead, Michael Tolentino
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2023-11-01
主題:	AMD (age-related macular degeneration) polysia mimetics nanoparticles macrophages Siglec
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1237016/full