Influenza Vaccination Results in Differential Hemagglutinin Stalk-Specific Fc-Mediated Functions in Individuals Living With or Without HIV

Influenza virus hemagglutinin (HA) stalk-specific antibodies have been shown to potently induce Fc-mediated effector functions which are important in protection from disease. In placebo-controlled maternal influenza (MatFlu) vaccination trials of pregnant women living with or without HIV, reduced ri...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Boitumelo M. Motsoeneng, Nisha Dhar, Marta C. Nunes, Florian Krammer, Shabir A. Madhi, Penny L. Moore, Simone I. Richardson
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-04-01
Subjects:	influenza vaccination Fc effector functions HIV co-infection hemagglutinin stalk antibodies antibody-dependent cellular phagocytosis (ADCP) antibody-dependent complement deposition (ADCD)
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.873191/full