Active metabolites as antidepressant drugs: The role of norquetiapine in the mechanism of action of quetiapine in the treatment of mood disorders

Active metabolites of some antipsychotic drugs exhibit pharmacodynamic and pharmacokinetic properties that may be similar to or differ from the original compound and that can be translated by a different profile of responses and interactions to clinical level. Some of these antipsychotics’ active me...

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Bibliographic Details

Published in:	Frontiers in Psychiatry
Main Authors:	Francisco eLopez-Munoz, Cecilio eAlamo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2013-09-01
Subjects:	Mood Disorders antipsychotic drugs quetiapine active metabolites norquetiapine
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00102/full