Early detection and prognosis evaluation for hepatocellular carcinoma by circulating tumour DNA methylation: A multicentre cohort study

Abstract Background Early diagnosis of hepatocellular carcinoma (HCC) can significantly improve patient survival. We aimed to develop a blood‐based assay to aid in the diagnosis, detection and prognostic evaluation of HCC. Methods A three‐phase multicentre study was conducted to screen, optimise and...

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Bibliographic Details

Published in:	Clinical and Translational Medicine
Main Authors:	De‐Zhen Guo, Ao Huang, Ying‐Chao Wang, Shuang Zhou, Hui Wang, Xiang‐Lei Xing, Shi‐Yu Zhang, Jian‐Wen Cheng, Ke‐Hui Xie, Qi‐Chang Yang, Cheng‐Cheng Ma, Qing Li, Yan Chen, Zhi‐Xi Su, Jia Fan, Rui Liu, Xiao‐Long Liu, Jian Zhou, Xin‐Rong Yang
Format:	Article
Language:	English
Published:	Wiley 2024-05-01
Subjects:	circulating tumour DNA methylation diagnosis hepatocellular carcinoma liquid biopsy prognosis
Online Access:	https://doi.org/10.1002/ctm2.1652