Platelet-rich plasma enhances local homing of umbilical cord-derived mesenchymal stem cells to articular cartilage by increasing the quantity and activation of integrin ꞵ1

Abstract Background Enhancing mesenchymal stem cells (MSCs) engraftment at the degenerative cartilage is important to increase the therapeutic effect of cartilage regeneration. Platelet-rich plasma (PRP) is known to have anti-inflammatory and anabolic effects for the treatment of osteoarthritis and...

Full description

Bibliographic Details

Published in:	Stem Cell Research & Therapy
Main Authors:	Min Ji Lee, Soo Hyun Kim, Sue Shin, Tae Woo Kim, Chris Hyunchul Jo
Format:	Article
Language:	English
Published:	BMC 2025-09-01
Subjects:	Cartilage regeneration Mesenchymal stem cells Homing Engraftment
Online Access:	https://doi.org/10.1186/s13287-025-04593-y