Effects of chemoradiotherapy on surface PD-L1 expression in esophageal cancer and its implications for immunotherapy

BackgroundEsophageal cancer has a poor prognosis despite treatment advancements. Although the benefit of neoadjuvant chemoradiotherapy (CRT) followed by adjuvant immunotherapy is evident, the effects of CRT on PD-L1 expression in esophageal cancer are not well understood. This study examines the imp...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Lovis Hampe, Stefan Küffer, Tim Niemeier, Niklas Christian Scheele, Laetitia Zoe Hampe, Anna Luisa Riedl, Laura Anna Fischer, David Alexander Ziegler, Martin Leu, Leif Hendrik Dröge, Alexander König, Michael Ghadimi, Friederike Braulke, Stefan Rieken, Hanibal Bohnenberger, Rami A. El Shafie
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-12-01
Subjects:	esophageal cancer immunotherapy programmed-death-ligand-1 checkmate-577 CROSS
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1509051/full