Administration of High-Dose Methylprednisolone Worsens Bone Loss after Acute Spinal Cord Injury in Rats

The administration of high-dose methylprednisolone (MP) for 24?48?h after traumatic spinal cord injury (SCI) has been shown to improve functional recovery. The known adverse effects of MP on skeletal muscle and the immune system, though, have raised clinically relevant safety concerns. However, the...

Full description

Bibliographic Details

Published in:	Neurotrauma Reports
Main Authors:	Yuanzhen Peng, Wei Zhao, Yizhong Hu, X. Edward Guo, Jun Wang, Ke Hao, Zhiming He, Carlos Toro, William A. Bauman, Weiping Qin
Format:	Article
Language:	English
Published:	Mary Ann Liebert 2021-12-01
Subjects:	bone loss bone resorption methylprednisolone receptor activator of NF-?B ligand spinal cord injury
Online Access:	https://www.liebertpub.com/doi/full/10.1089/NEUR.2021.0035