Nicotinamide N-methyltransferase (NNMT): a novel therapeutic target for metabolic syndrome

Metabolic syndrome (MetS) represents a constellation of metabolic abnormalities, typified by obesity, hypertension, hyperglycemia, and hyperlipidemia. It stems from intricate dysregulations in metabolic pathways governing energy and substrate metabolism. While comprehending the precise etiological m...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Wei-Dong Sun, Xiao-Juan Zhu, Jing-Jing Li, Ya-Zhong Mei, Wen-Song Li, Jiang-Hua Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-06-01
Subjects:	nicotinamide N-methyltransferase (NNMT) metabolic syndrome (MetS) nicotinamide adenine dinucleotide (NAD+) homocysteine (Hcy) obesity diabetes
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1410479/full