The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans.

Intestinal epithelial cells are subject to attack by a diverse array of microbes, including intracellular as well as extracellular pathogens. While defense in epithelial cells can be triggered by pattern recognition receptor-mediated detection of microbe-associated molecular patterns, there is much...

Full description

Bibliographic Details
Published in:PLoS Pathogens
Main Authors: Eillen Tecle, Crystal B Chhan, Latisha Franklin, Ryan S Underwood, Wendy Hanna-Rose, Emily R Troemel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Online Access:https://doi.org/10.1371/journal.ppat.1009350