Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure

Oxidative stress provokes endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) in the lungs of chronic obstructive pulmonary (COPD) subjects. The antioxidant, glutathione peroxidase-1 (GPx-1), counters oxidative stress induced by cigarette smoke exposure. Here, we investigate wh...

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Bibliographic Details

Published in:	Mediators of Inflammation
Main Authors:	Patrick Geraghty, Nathalie Baumlin, Matthias A. Salathe, Robert F. Foronjy, Jeanine M. D’Armiento
Format:	Article
Language:	English
Published:	Wiley 2016-01-01
Online Access:	http://dx.doi.org/10.1155/2016/9461289