Hierarchical network modulation of cell death regulators and inflammatory genes by biogenically engineered gold nanoconstructs with CK in gastric tumorigenesis

Abstract Background Gastric cancer (GC) progression is influenced through the dysregulation of the cell death and chronic inflammation, which together foster a tumor-promoting microenvironment and enhance cancer cell survival. Targeting these pathways could provide novel therapeutic strategies. In a...

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Bibliographic Details

Published in:	Cancer Nanotechnology
Main Authors:	Abdus Samad, Abishek Gnanasekaran, Yeon Ju Kim
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Subjects:	Biogenic nano-construct Cell death (apoptosis/ferroptosis/necrosis) Inflammation Gastroepithelial transcriptomic dysregulation RNA sequencing
Online Access:	https://doi.org/10.1186/s12645-025-00310-9