Methylome-wide association study of different responses to risperidone in schizophrenia

Background: Accumulating evidence shows that DNA methylation plays a role in antipsychotic response. However, the mechanisms by which DNA methylation changes are associated with antipsychotic responses remain largely unknown.Methods: We performed a methylome-wide association study (MWAS) to evaluate...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Huihui Du, Jingsong Ma, Wei Zhou, Mo Li, Cong Huai, Lu Shen, Hao Wu, Xianglong Zhao, Na Zhang, Songyin Gao, Qi Wang, Lin He, Xuming Wu, Shengying Qin, Mingzhe Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Subjects:	pharmacoepigenomics antipsychotic response MWAS DMP DMR
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1078464/full