Functional Interaction Between Caveolin 1 and LRRC8-Mediated Volume-Regulated Anion Channel

Volume-regulated anion channel (VRAC), constituted by leucine-rich repeat-containing 8 (LRRC8) heteromers, is crucial for volume homeostasis in vertebrate cells. This widely expressed channel has been associated with membrane potential modulation, proliferation, migration, apoptosis, and glutamate r...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Mikel Rezola, Aida Castellanos, Xavier Gasull, Núria Comes
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Subjects:	volume-regulated anion channel LRRC8A caveolins swelling-activated chloride current protein interaction channel surface localization
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2021.691045/full