Remimazolam alleviates hippocampal neuronal injury in an in vitro Alzheimer’s disease model by promoting PINK1/Parkin-mediated mitophagy

Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the pathological accumulation of amyloid-β (Aβ) plaques and hyperphosphorylated tau proteins. Remimazolam (RMZ), a novel ultra-short-acting benzodiazepine, exhibits neuroprotective effects by enhancing mit...

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Bibliographic Details

Published in:	European Journal of Medical Research
Main Authors:	Wei Zhang, Bowen Shi, Yuanyuan Xie, Yan Li, Jianke Yang, Ke Zhao
Format:	Article
Language:	English
Published:	BMC 2025-10-01
Subjects:	Remimazolam Mitophagy PINK1/Parkin pathway Alzheimer’s disease
Online Access:	https://doi.org/10.1186/s40001-025-03179-x