Homer1a reduces inflammatory response after retinal ischemia/reperfusion injury

Elevated intraocular pressure (IOP) is one of the causes of retinal ischemia/reperfusion injury, which results in NLRP3 inflammasome activation and leads to visual damage. Homer1a is reported to play a protective role in neuroinflammation in the cerebrum. However, the effects of Homer1a on NLRP3 inf...

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Bibliographic Details

Published in:	Neural Regeneration Research
Main Authors:	Yanan Dou, Xiaowei Fei, Xin He, Yu Huan, Jialiang Wei, Xiuquan Wu, Weihao Lyu, Zhou Fei, Xia Li, Fei Fei
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2024-01-01
Subjects:	caspase-8; homer1a; interleukin-18; interleukin-1β; intraocular pressure; ischemia/reperfusion injury; jsh-23; müller cells; nlrp3; nuclear factor-kb p65; retina
Online Access:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=7;spage=1608;epage=1617;aulast=Dou