A Novel Frizzled-Based Screening Tool Identifies Genetic Modifiers of Planar Cell Polarity in Drosophila Wings

Most mutant alleles in the Fz-PCP pathway genes were discovered in classic Drosophila screens looking for recessive loss-of-function (LOF) mutations. Nonetheless, although Fz-PCP signaling is sensitive to increased doses of PCP gene products, not many screens have been performed in the wing under ge...

Full description

Bibliographic Details
Published in:G3: Genes, Genomes, Genetics
Main Authors: Jose Maria Carvajal-Gonzalez, Sonia Mulero-Navarro, Michael Smith, Marek Mlodzik
Format: Article
Language:English
Published: Oxford University Press 2016-12-01
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.035535