Pre-clinical xenotransplantation: physiology and pharmacy in human decedent and non-human primate models

Non-human primates and decedent humans have emerged as the two principal translational models in xenotransplantation. Each model has differing advantages and drawbacks. In this manuscript, we will compare and contrast the relative strengths of each model, focusing on the physiologic function of the...

Full description

Bibliographic Details

Published in:	Frontiers in Transplantation
Main Authors:	Douglas J. Anderson, Jayme E. Locke
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	xenotransplant kidney renal physiology pharmacokinetics non-human primate decedent model
Online Access:	https://www.frontiersin.org/articles/10.3389/frtra.2025.1576549/full