TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors

Understanding the processes that govern liver progenitor cell differentiation has important implications for the design of strategies targeting chronic liver diseases, whereby regeneration of liver tissue is critical. Although DNA methylation (5mC) and hydroxymethylation (5hmC) are highly dynamic du...

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Bibliographic Details

Published in:	Stem Cell Reports
Main Authors:	Pierre-Benoit Ancey, Szilvia Ecsedi, Marie-Pierre Lambert, Fazlur Rahman Talukdar, Marie-Pierre Cros, Denise Glaise, Diana Maria Narvaez, Veronique Chauvet, Zdenko Herceg, Anne Corlu, Hector Hernandez-Vargas
Format:	Article
Language:	English
Published:	Elsevier 2017-07-01
Subjects:	liver progenitor DNA methylation 5mC 5hmC HNF4A
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213671117302308