Inhaling arsenic aggravates airway hyperreactivity by upregulating PNEC-sourced 5-HT in OVA-induced allergic asthma

Increasing epidemiological evidence has proved that early-life exposure to inorganic arsenic (As) elevates the risks of childhood asthma. The present research aimed to explore susceptibility of respiratory As exposure to allergic asthma in a mouse model. BALB/c mice on postnatal day (PND) 28 were ex...

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Bibliographic Details

Published in:	Ecotoxicology and Environmental Safety
Main Authors:	Xue Lu, Zhu-Xia Tan, Ya-Xin Yao, Ze-Yan Li, Yan-Yan Zhu, Qian-Qun Yang, Zhao Li, Kun Peng, Yan Wang, De-Xiang Xu
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Subjects:	Arsenic Respiratory tract Allergic asthma Airway hyperreactivity Pulmonary neuroendocrine cell 5-hydroxytryptamine
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651325001009